{"id":22178,"date":"2022-06-30T17:03:53","date_gmt":"2022-06-30T15:03:53","guid":{"rendered":"https:\/\/www.pancosma.com\/?p=22178"},"modified":"2022-07-05T12:38:50","modified_gmt":"2022-07-05T10:38:50","slug":"novel-yeast-supports-broilers-in-necrotic-enteritis-challenge","status":"publish","type":"post","link":"https:\/\/www.pancosma.com\/es\/novel-yeast-supports-broilers-in-necrotic-enteritis-challenge\/","title":{"rendered":"Novel yeast supports broilers in necrotic enteritis challenge"},"content":{"rendered":"

Case study<\/strong> describing the response of broilers to a novel yeast in their diet during a necrotic enteritis challenge.<\/p>\n

Published in Livestock and Feed Business, June 2022<\/p>\n

Author: Sarah Cooper<\/strong><\/p>\n

Pathogenic and physiological challenges are ubiquitous in animal production systems as they threaten efficient and profitable production. Tools (like growth-promoting antibiotics and ionophores) once used to improve production efficiency are increasingly being restricted. As such, there is a growing interest in evolved management and nutritional practices.<\/p>\n

Yeasts have been fed to animals for over 100 years due to their nutritional richness and reported effects to support health and growth performance. Saccharomyces cerevisiae <\/em>is the most used yeast in animal feed applications. Yeast cell walls contain various bioactive components like \u00df-glucans and mannan oligosaccharides, which have shown to have beneficial impacts across various species. Several studies revealed that dietary \u00df-glucans interact with intestinal cells affecting the modulation of the intestinal immune response.\u00a0Mannan oligosaccharides have also been demonstrated to bind and limit the colonisation of intestinal pathogens with beneficial consequences related to gastrointestinal health and ensuing performance.<\/p>\n

Pichia<\/em><\/strong> guilliermondii<\/em><\/strong>,<\/strong> an<\/strong> extraordinary <\/strong>yeast<\/strong><\/h3>\n

Pichia guilliermondii <\/em>is a novel yeast with unique morphology, structure and consequent activity. The way yeast cells in animal feed behave in the animal\u2019s intestinal environment (interacting with intestinal epithelium and luminal contents) depends on the morphology, cell wall structure and composition.<\/p>\n

The comparative morphology and physical characteristics of P.<\/em> guilliermondii <\/em>and S. cerevisiae <\/em>were assessed in a side-by- side study. There are significant differences between them: P. guilliermondii <\/em>is a smaller cell and has a greater surface area to volume ratio. It is also more hydrophobic compared to S. cerevisiae<\/em>.<\/p>\n

Additionally, the distribution of various glycoproteins in the yeast cell wall varies, suggesting that P. guilliermondii <\/em>has a different cell wall structure and composition to S. cerevisiae<\/em>. These particularities may be associated with significant differences in how\u00a0both yeast cells behave when used in animal feeds.<\/p>\n

The function of P. guilliermondii and <\/em>associated influence on physiological and performance parameters have been assessed across various animal species. This body of research has focused on exploring the impact that may be associated with P.<\/em> guilliermondii <\/em>on the immune system, pathogen load,\u00a0gastrointestinal health and performance, especially during stress and pathogenic challenges.<\/p>\n

Pichia<\/strong> in<\/strong> action:<\/strong> A<\/strong> broiler<\/strong> case<\/strong> study for necrotic enteritis challenge<\/strong><\/h3>\n

Coccidiosis and necrotic enteritis represent the greatest threat to poultry production globally, being detrimental to animal welfare and having economic impacts.<\/p>\n

In an experimental necrotic enteritis study with broilers, birds that received P. guilliermondii supplementation showed indications of increased resilience and improved performance compared to control birds that did not receive any P. guilliermondii <\/em>in their diet.<\/p>\n

In this 42-day long study, newly hatched Ross 708 broilers were assigned to either the three-phase basal control diet or the three-phase basal diet plus 0.1% P. <\/em>guilliermondi<\/em>i until day 28, then 0.075% P. <\/em>guilliermondii <\/em>until day 42.<\/p>\n

The necrotic enteritis challenge consisted of adding used litter to introduce coccidia on day 4 and challenging birds with Clostridium perfringens on days 17, 18 and 19.<\/p>\n

A group of birds on the basal control diet did not receive the challenge and acted as the non-infected control group. On day 21, birds from each group were randomly selected and euthanised, with their intestines examined for necrotic enteritis\u00a0lesions. Lesion scores range from 0 (for normal) to 4 (for the most severe lesions).<\/p>\n

Birds receiving P.<\/em> guilliermondii<\/em> in their diet had lower intestinal lesions compared to challenged birds receiving only the control diet. The significantly lower intestinal lesion scores in the P. guilliermondii<\/em>-fed birds suggest greater physiological resilience\u00a0 in the face of the necrotic enteritis challenge, compared to the birds with more severe lesion scores in the infected control group.\u00a0 At the end of the study, on day 42, P. guilliermondii<\/em>– supplemented birds had improved performance parameters compared to the infected control group. The adjusted feed conversion ratio was better in the group that had received P.guilliermondii <\/em>in their diet. These birds also had a significantly greater body weight. Of note, day 42 mortality was numerically lower in the P. guilliermondii <\/em>group compared to the infected control group.<\/p>\n

P. guilliermondii <\/em>has unique morphological properties influencing its efficacy in animal feeding. Research has demonstrated that the addition of P. guilliermondii <\/em>to the diet of broilers may be associated with beneficial impacts on parameters in the face of coccidiosis and necrotic enteritis<\/p>\n

 <\/p>\n

Relevant articles<\/h3>\n

Webinar recording – Necrotic enteritis advances in control<\/a><\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Case study describing the response of broilers to a novel yeast in their diet during a necrotic enteritis challenge. Published in Livestock and Feed Business, June 2022 Author: Sarah Cooper Pathogenic and physiological challenges are ubiquitous in animal production systems as they threaten efficient and profitable production. Tools (like growth-promoting antibiotics and ionophores) once used […]<\/p>\n","protected":false},"author":16,"featured_media":22184,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[3170,3173,3209],"tags":[],"class_list":["post-22178","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-blog","category-poultry","category-publications"],"acf":[],"yoast_head":"\nNovel yeast supports broilers in necrotic enteritis challenge - Pancosma<\/title>\n<meta name=\"description\" content=\"Case study describing the response of broilers to a novel yeast in their diet during a necrotic enteritis challenge\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pancosma.com\/novel-yeast-supports-broilers-in-necrotic-enteritis-challenge\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Novel yeast supports broilers in necrotic enteritis challenge - 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